Mapping Metabolic Drivers of Disease Using Chemoproteomic and Metabolomic Platforms

Friday, October 9, 2015 - 2:00pm
Fung Auditorium, Powell-Focht Bioengineering Hall
Daniel Nomura

Assistant Professor
Department of Nutritional Science and Toxicology
University of California, Berkeley

Mapping Metabolic Drivers of Disease Using Chemoproteomic and Metabolomic Platforms

Abstract: 
The Nomura Research Group is focused on developing and utilizing chemical proteomic and metabolomic systems biology platforms to identify critical metabolic nodes and chemical-protein interactions that drive human diseases and chemically-induced adverse health effects. Our laboratory currently has two major research areas. Our first research area focuses on utilizing chemoproteomic and metabolomic platforms to map dysregulated metabolism in complex human diseases towards identifying unique and novel therapeutic strategies that target key nodes in metabolic pathways. Our second research area focuses around developing innovative chemoproteomic and metabolomic strategies for comprehensive assessment of chemical toxicology ranging from small-molecule target identification, target characterization, and predictive and mechanistic toxicological assessment.
Bio: 

Dan Nomura is a UC Berkeley faculty member in the metabolic biology program in the Department of Nutritional Sciences and Toxicology. He earned his Ph.D in molecular toxicology at Berkeley and was a postdoctoral fellow in chemical physiology at The Scripps Research Institute before returning to Berkeley as a faculty member in 2011. Among his honors are selection as a Searle Scholar, American Cancer Society Research Scholar Award, and the DOD Breakthroughs Award.