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February 10, 2022
Simplifying RNA editing for treating genetic diseases
New research led by bioengineers at the University of California San Diego could make it much simpler to repair disease-causing mutations in RNA without compromising precision or efficiency. The new RNA editing technology holds promise as a gene therapy for treating genetic diseases. In a proof of concept, UC San Diego researchers showed that the technology can treat a mouse model of Hurler syndrome, a rare genetic disease, by correcting its disease-causing mutation in RNA. Full Story
February 9, 2022
Mapping mutation 'hotspots' in cancer reveals new drivers and biomarkers
UC San Diego researchers have identified a previously unrecognized key player in cancer evolution: clusters of mutations occurring at certain regions of the genome. These mutation clusters contribute to the progression of about 10% of human cancers and can be used to predict patient survival. Full Story
January 27, 2022
New drug screening method answers why Alzheimer's drugs fail, suggests new targets
A study led by UC San Diego sheds light on why Alzheimer’s drugs so far have been ineffective at curing or reversing the disease. The researchers identify new targets for drug development and present a new method to screen drugs for treating Alzheimer's disease. Full Story
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