Shaochen Chen
Professor and Vice Chair of NanoEngineering Department
Professor of Bioengineering and Radiology Departments
Founding Co-Director of Biomaterials & Tissue Engineering Center
University of California, San Diego
Seminar Information
In this talk, I will present our laboratory’s recent research efforts in rapid 3D bioprinting to create 3D tissue constructs using a variety of biomaterials and cells. These 3D biomaterials are functionalized with precise control of micro-architecture, mechanical (e.g. stiffness), chemical, and biological properties [1]. Such functional biomaterials allow us to investigate cell-microenvironment interactions at nano- and micro-scales in response to integrated physical and chemical stimuli. From these fundamental studies we have been creating both in vitro and in vivo precision tissues for tissue regeneration, disease modeling, and drug discovery [2,3]. To vascularize these engineered tissues, we have also developed a prevascularization technique by using the rapid 3D bioprinting method [4]. Multiple cell types mimicking the native vascular cell composition were encapsulated directly into hydrogels with precisely controlled distribution.
Dr. Shaochen Chen is a Professor and Vice Chair in the NanoEngineering Department and Affiliate Professor in the Bioengineering Department at the University of California, San Diego (UCSD). He is the founding co-director of the Biomaterials and Tissue Engineering Center at UCSD. Before joining UCSD, Dr. Chen had been a Professor and a Henderson Centennial Endowed Faculty Fellow in Engineering at the University of Texas at Austin from 2001 to 2010. Between 2008 and 2010, he served as the Program Director for the Nanomanufacturing Program of the National Science Foundation (NSF). Dr. Chen’s primary research interests include: 3D printing and bioprinting, biomaterials and nanomaterials, stem cell and regenerative medicine, tissue engineering. He has published over 140 papers in top journals. Among his numerous awards, Dr. Chen received the NSF CAREER award, ONR Young Investigator award, and NIH Edward Nagy New Investigator Award. He also received the Milton C. Shaw Manufacturing Research Medal from ASME for his seminal work in 3D printing, bioprinting, and nanomanufacturing. Dr. Chen is a Fellow of AAAS, AIMBE, ASME, SPIE, and ISNM.