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An Interview with 2014 Research Expo Winner Ya-San Yeh

May 12, 2014

An Interview with 2014 Research Expo Winner Ya-San Yeh

Ya-San Yeh, a University of California, San Diego Jacobs School of Engineering graduate student won the grand prize at Research Expo 2014 on April 17 for her research on silica nanoparticles for cancer treatment. Yeh received the Rudee Outstanding Poster Award as well as the best departmental poster in bioengineering.  We caught up with Yeh after the big win to talk about her research and what it is like to work on a problem as big as cancer. Updated May 14 with videos of Research Expo faculty talks.  Full Story


 Nanoengineers develop basis for electronics that stretch at the molecular level

May 6, 2014

Nanoengineers develop basis for electronics that stretch at the molecular level

Nanoengineers at the University of California, San Diego are asking what might be possible if semiconductor materials were flexible and stretchable without sacrificing electronic function? Full Story


Silica Nanoparticles for Cancer Treatment Take Top Prize at Research Expo 2014

April 18, 2014

Silica Nanoparticles for Cancer Treatment Take Top Prize at Research Expo 2014

Ya-San Yeh, a University of California, San Diego graduate student working in the laboratory of electrical engineering and nanoengineering professor Sadik Esener, won the grand prize at Research Expo 2014 for her research on silica nanoparticles for cancer treatment. Yeh received the Rudee Outstanding Poster Award as well as the best departmental poster in bioengineering. Full Story


Researchers Develop Bacterial 'FM Radio'

April 9, 2014

Researchers Develop Bacterial 'FM Radio'

Programming living cells offers the prospect of harnessing sophisticated biological machinery for transformative applications in energy, agriculture, water remediation and medicine.  Inspired by engineering, researchers in the emerging field of synthetic biology have designed a tool box of small genetic components that act as intracellular switches, logic gates, counters and oscillators. But scientists have found it difficult to wire the components together to form larger circuits that can function as “genetic programs.”  One of the biggest obstacles? Dealing with a small number of available wires. A team of biologists and engineers at UC San Diego has taken a large step toward overcoming this obstacle. Their advance, detailed in a paper which appears in this week’s advance online publication of the journal Nature, describes their development of a rapid and tunable post-translational coupling for genetic circuits. This advance builds on their development of “biopixel” sensor arrays reported in Nature by the same group of scientists two years ago. Full Story


Engineering a New Biomaterial Therapy for Treating Heart Attacks

April 4, 2014

Engineering a New Biomaterial Therapy for Treating Heart Attacks

Bioengineering professor Karen Christman's new injectable hydrogel, which is designed to repair damaged cardiac tissue following a heart attack, has been licensed to San Diego-based startup Ventrix, Inc, which is planning the first human clinical trials of the technology. Full Story


Understanding How the Brain Controls Movement

April 2, 2014

Understanding How the Brain Controls Movement

A University of California, San Diego research team led by bioengineering professor Gert Cauwenberghs is working to understand how the brain circuitry controls how we move. The goal is to develop new technologies to help patients with Parkinson's disease and other debilitating medical conditions navigate the world on their own. Their research is funded by the National Science Foundation’s Emerging Frontiers of Research and Innovation program. Full Story


Cymer Co-Founder Richard Sandstrom and Wife, Sandra Timmons, Give $1.2 Million for Students

March 27, 2014

Cymer Co-Founder Richard Sandstrom and Wife, Sandra Timmons, Give $1.2 Million for Students

University of California, San Diego alumni Sandra Timmons and Richard Sandstrom, co-founder of Cymer, Inc., are passionate about their alma mater and helping future students achieve the same world-class education they received at UC San Diego. That’s why the couple recently pledged a gift of $1.2 million to the campus for student support through their charitable Timmstrom Family Fund. The gift will be split, per the donors’ wishes, to support graduate students in the Jacobs School of Engineering and undergraduates through the Chancellor’s Associates Scholars program. Full Story


It's a bird! It's a plane! It's a...pie?

March 26, 2014

It's a bird! It's a plane! It's a...pie?

Move over watermelons and pumpkins! There’s a new addition to the list of things that are being dropped from the top of UC San Diego’s buildings—pie. To be more precise, a 13-inch, 4.5 pounds cherry pie from Costco, which was dropped from the third floor of the Structural and Materials Engineering building. It was all part of Pi Day celebrations March 14 at the Jacobs School of Engineering at UC San Diego. Fun for the day also included the third annual Pi-Mile Run and Walk, which set a record for turnout, with more than 200 people taking part.  Full Story


Study finds that fast-moving cells in the human immune system walk in a stepwise manner

March 17, 2014

Study finds that fast-moving cells in the human immune system walk in a stepwise manner

A team of biologists and engineers at UC San Diego applied advanced mathematical tools to answer a basic question in cell biology about how cells move and discovered that the mechanism looks very similar to walking. Their discovery, published March 17 in the Journal of Cell Biology, is an important advance toward developing new pharmacological strategies to treat chronic inflammatory diseases. Full Story


New UC San Diego Biosensor Will Guard Water Supplies from Toxic Threats

March 11, 2014

New UC San Diego Biosensor Will Guard Water Supplies from Toxic Threats

Supported by a $953,958 grant from the Defense Advanced Research Projects Agency (DARPA), researchers at the University of California San Diego will develop a sophisticated new biosensor that can protect the nation’s water supplies from a wide range of toxins, including heavy metals and other poisons. The project, led by Jeff Hasty, director of the BioCircuits Institute at UC San Diego, will combine next-generation sequencing, synthetic biology, and microfluidic technologies to engineer a highly specific array of biosensors that will continuously monitor water supplies for the presence of toxins. Full Story


Dive into Technology's Future at Research Expo 2014

March 7, 2014

Dive into Technology's Future at Research Expo 2014

Research Expo will be held on Thursday, April 17, from 1:30 p.m. to 6p.m. Register today. The annual event features research posters by more than 200 engineering graduate students from UC San Diego, faculty talks, and a networking reception with faculty, students, industry partners and alumni. Full Story


Color Block

February 28, 2014

Bioengineering Students Recognized for Outstanding Research

Several bioengineering students have been recognized for their outstanding research. Full Story


Studying Stem Cell Diets to Make Better Heart Cells

January 30, 2014

Studying Stem Cell Diets to Make Better Heart Cells

What nutrients are needed for stem cells to grow and function as heart cells? That’s the question at the heart of research led by bioengineer Christian Metallo at the University of California, San Diego. He is one of eight UC San Diego researchers to receive a combined total of $8.165 million in funding from the California Institute for Regenerative Medicine in a new round of Basic Biology awards announced Jan. 29.  Metallo’s share is $1.124 million. The awards were made by CIRM’s Independent Citizens Oversight Committee. Full Story


UC San Diego Highlighted in Governor's State of the State Address

January 24, 2014

UC San Diego Highlighted in Governor's State of the State Address

As Governor Edmund G. Brown Jr. delivered his annual State of the State address to the Legislature yesterday, he highlighted the University of California, San Diego as a leader in developing medical and scientific advances. In prepared remarks, Gov. Brown noted, “Four out of the world’s 20 leading academic bioscience institutions are located here in California: UCSF and Berkeley, UCLA, Stanford and UC San Diego. Just as California has led the way with stem cell research, so too can we pioneer the new field of precision medicine which uses genomics, medical devices, computer sciences and other fields to treat individual patients, instead of broad populations.” Full Story


Single-Cell Genome Sequencing Gets Better

January 14, 2014

Single-Cell Genome Sequencing Gets Better

Bioengineers at the Jacobs School have created a better way to sequence genomes from individual cells. The breakthrough, which relies on microwells just 12 nanoliters in volume (see image below), is one of many recent "omics" innovations from researchers across the Jacobs School and UC San Diego. The single-cell genome sequencing advance from Kun Zhang's lab could help researchers understand what causes Alzheimer's disease. The work could also enable scientists to identify tough-to-culture microbes living in ocean water and within the human body-by probing single cells. Full Story


Color Block

January 9, 2014

How to Manage Mobile Medical App Development Under FDA Regulation

A consortium of six leading universities, more than a dozen industry trade associations and professional societies, and the U.S. Food & Drug Administration announced their unprecedented collaboration to develop a series of educational programs designed to help mobile app developers learn about FDA requirements for producing higher risk medical apps as well as the business issues associated with entering this space.Called the “MMA Roadshow:  Managing App Development under FDA Regulation,” the four-hour workshops are scheduled over several months across the country, including Jan. 27 at the University of California, San Diego. Full Story


Biomaterials Get Stem Cells to Commit to a Bony Future

January 6, 2014

Biomaterials Get Stem Cells to Commit to a Bony Future

With the help of biomimetic matrices, a research team led by bioengineers at the University of California, San Diego has discovered exactly how calcium phosphate can coax stem cells to become bone-building cells. This work is published in the Proceedings of the National Academy of Sciences the week of Jan. 6, 2014. Full Story


2013: The Year in Review

December 13, 2013

2013: The Year in Review

From the largest alumni gift in the campus’ history, which went to the Department of Computer Science and Engineering, to the arrival of Dean Al Pisano, it’s been a busy year here at the Jacobs School of Engineering. The school produced many research milestones, from a Google map of the human metabolism to the world’s first zoomable contact lens. Students got into the action too and UC San Diego became the first university to design, build and test a 3D-printed rocket engine. Here are some of the most memorable stories of the year—but not all: the list would be too long.  Full Story


Bioengineering Professor Among Six UC San Diego Faculty Named 2013 AAAS Fellows

November 25, 2013

Bioengineering Professor Among Six UC San Diego Faculty Named 2013 AAAS Fellows

Six professors at the University of California, San Diego have been named 2013 Fellows of the American Association for the Advancement of Science, the nation’s largest general science organization. Full Story


New Models Predict Where E. coli Strains Will Thrive

November 18, 2013

New Models Predict Where E. coli Strains Will Thrive

Bioengineers at the University of California, San Diego have used the genomic sequences of 55 E. coli strains to reconstruct the metabolic repertoire for each strain. Surprisingly, these reconstructions do an excellent job of predicting the kind of environment where each strain will thrive, the researchers found. Their analysis, published in the Nov. 18, 2013 early edition of the Proceedings of the National Academy of Sciences, could prove useful in developing ways to control deadly E. coli infections and to learn more about how certain strains of the bacteria become virulent. Full Story