News

UC San Diego Scientists Create Device for Ultra-Accurate Genome Sequencing of Single Human Cells

October 31, 2017

UC San Diego Scientists Create Device for Ultra-Accurate Genome Sequencing of Single Human Cells

An interdisciplinary team of researchers at the University of California San Diego has developed a technology for very accurate sequencing and haplotyping of genomes from single human cells. Their findings were published online in advance of the Proceedings of the National Academy of Sciences (PNAS)* print edition.“Accurate sequencing of single cells will enable the identification of mutations that cause cancer and genetic disease,” said senior author Kun Zhang, a professor of bioengineering in the UC San Diego Jacobs School of Engineering. “At the same time, precise haplotyping will allow for the genotyping of haplotypes, combinations of different genes or alleles as a group from either parent.” Full Story


Model predicts how E. coli bacteria adapt under stress

October 13, 2017

Model predicts how E. coli bacteria adapt under stress

Researchers at UC San Diego have developed a genome-scale model that can accurately predict how E. coli bacteria respond to temperature changes and genetic mutations. The work sheds light on how cells adapt under environmental stress and has applications in precision medicine, where adaptive cell modeling could provide patient-specific treatments for bacterial infections.  Full Story


Smart molecules trigger white blood cells to become better cancer-eating machines

September 28, 2017

Smart molecules trigger white blood cells to become better cancer-eating machines

A team of researchers has engineered smart protein molecules that can reprogram white blood cells to ignore a self-defense signaling mechanism that cancer cells use to survive and spread in the body. Researchers say the advance could lead to a new method of re-engineering immune cells to fight cancer and infectious diseases. The team successfully tested this method in a live cell culture system.  Full Story


Undergraduate Bioengineering Program at UC San Diego Ranks #6 in the Nation and #2 among Public Engineering Schools

September 12, 2017

Undergraduate Bioengineering Program at UC San Diego Ranks #6 in the Nation and #2 among Public Engineering Schools

The U.S. News and World Report Best Colleges guidebook rankings are out today and the bioengineering undergraduate program at the University of California San Diego Jacobs School of Engineering is ranked #6 in the nation and #2 among public schools. Full Story


Four Physician-Engineer Teams Funded by UC San Diego

August 25, 2017

Four Physician-Engineer Teams Funded by UC San Diego

Four physician-engineer teams from UC San Diego have been selected to receive the 2017 Galvanizing Engineering in Medicine (GEM) awards. This is an initiative of UC San Diego Altman Clinical and Translational Research Institute (ACTRI) and UC San Diego Institute of Engineering in Medicine (IEM). It brings engineers and clinicians together to develop innovative technologies that can be applied to solving challenging problems in medical care. This year’s projects address challenges in the areas of cardiology, ophthalmology, radiology, and reproductive medicine. Full Story


Help UC San Diego Scientists Study Link between Body Bacteria and Autoimmune Diseases

August 23, 2017

Help UC San Diego Scientists Study Link between Body Bacteria and Autoimmune Diseases

The public's help is being enlisted in the Microbiome Immunity Project, what's thought to be the biggest study to date of the human microbiome — the communities of bacteria and other microbes that live in and on the human body, where they influence our health.  Full Story


Nature Names UC San Diego a Top 15 Research Institution Worldwide

August 9, 2017

Nature Names UC San Diego a Top 15 Research Institution Worldwide

The University of California San Diego is the world’s 14th best university for developing research that is used to create products or services that benefit society and spur economic growth. The new rankings by Nature, one of the world’s leading academic journals, also praise the campus for its research output: nearly half of UC San Diego’s natural science papers appear in the Nature index, which measures research productivity in the globe’s top science journals.  Full Story


Engineers harness the power of 3D printing to help train surgeons, shorten surgery times

August 2, 2017

Engineers harness the power of 3D printing to help train surgeons, shorten surgery times

A team of engineers and pediatric orthopedic surgeons are using 3D printing to help train surgeons and shorten surgeries for the most common hip disorder found in children ages 9 to 16. In a recent study, researchers showed that allowing surgeons to prep on a 3D-printed model of the patient’s hip joint cut by about  25 percent the amount of time needed for surgery when compared to a control group. The team, which includes bioengineers from the University of California San Diego and physicians from Rady Children’s Hospital, detailed their findings in a recent issue of the Journal of Children’s Orthopaedics.  Full Story


Scientists at the UC San Diego Center for Microbiome Innovation invent new tool for the Synthetic Biologist's toolbox

July 10, 2017

Scientists at the UC San Diego Center for Microbiome Innovation invent new tool for the Synthetic Biologist's toolbox

Researchers at the University of California San Diego have invented a new method for controlling gene expression across bacterial colonies. The method involves engineering dynamic DNA copy number changes in a synchronized fashion. The results were published in the July 10, 2017 online edition of Nature Genetics. Full Story


Bioengineering Professor Christian Metallo Receives 2017 Camille Dreyfus Teacher-Scholar Award

May 10, 2017

Bioengineering Professor Christian Metallo Receives 2017 Camille Dreyfus Teacher-Scholar Award

Christian Metallo, a bioengineering professor at the University of California San Diego, has been named a Camille Dreyfus Teacher-Scholar. Metallo is one of 13 faculty members nationwide to receive the honor from the Camille and Henry Dreyfus Foundation. Full Story